Effect of Ethanol Leaves Extract of Anthocleista vogelii and Cocos nucifera Water on Some Haematological Indices in Wistar Rats

Aim: To evaluate the effect of ethanol leaves extract of Anthocleista vogelii and Cocos nucifera water on haematological parameters in wistar rats.

Study Design: Haematology.

Place and Duration of Study: Department of Pharmacology and Therapeutics, Delta State University, Abraka Delta State, Nigeria, between July and August, 2015.

Methodology: Thirty rats divided into six groups of five were used for the study. Doses of 10 ml/kg of Cocos nucifera, 200 mg/kg, and 400 mg/kg of Anthocleista vogelii, and 200 mg/kg and 400 mg/kg of Anthocleista vogelii combination with Cocos nucifera (1:1) were administered to the animals, while the control group received normal saline (10 ml/kg). The experimental animals were administered the extracts orally once daily for 2 weeks according to their body weights, after which blood samples were obtained for haematological analysis.

Results: Anthocleista vogelii and Cocos nucifera extracts showed significant (P<0.05) increase in RBC, WBC, and PCV values.

Conclusion: The ethanol leaves extract of Anthocleista vogelii and its combination with Cocos nucifera water has positive haematopoietic effects.