THERAPEUTIC EFFICACY OF KABASURA KUDINEER (SIDDHA FORMULATION), IN COVID-19 – A REVIEW OF CLINICAL AND MOLECULAR DOCKING STUDIES

Coronavirus disease 2019 (COVID-19), which is brought about by novel coronavirus or Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) could be managed mainly by using repurposed antiviral drugs. This review focuses on the utilization of Kabasura Kudineer in asymptomatic or mild symptomatic COVID-19 patients. The databases such as Medline/PubMed Central/PubMed, Google Scholar, Science Direct, EBSCO, Scopus, Web of science, EMBASE, Directory of open access journals (DOAJ), and reference lists have been looked to distinguish articles pertinent to the clinical and in-silico studies assessing the efficacy of Kabasura Kudineer in the management of COVID-19. A few clinical investigations have exhibited the adequacy of Kabasura Kudineer in the management of asymptomatic or mild-symptomatic COVID-19 patients alongside standard care. Additionally, numerous molecular docking studies have been performed to determine the inhibitory capability of phytoconstituents of Kabasura Kudineer against SARS-CoV-2. More randomized controlled clinical trials would further establish the safety and efficacy of Kabasura Kudineer in COVID-19 patients.